& [19] [22] Studies of estrogenic activity and reproductive effects of oxybenzone found that oxybenzone can alter reproductive endpoints in fish species. [35] The federal OSHA Hazard Communication Standard (29 CFR 1910.1200) and the PEOSH Hazard Communication Standard (N.J.A.C. The K for benzophenone is 9.8 °C/m. [16] However, studies of benzophenone in juvenile female rats conclude that benzophenone s not estrogenic itself, but may become estrogenic when it is metabolized by the body into other chemicals (for instance, the benzophenone metabolite p-hydrosybenzophenone is estrogenic). BP2 affects ovaries of female fish and testes of male fish, and also reduces production of eggs and sperm. What is the lowest possible melting point for ice that could be obtained considering the solubility of NaCl in water? [8] Derivatives of benzophenones such as BP2 and oxybenzone (BP3) are used in sunscreens. Choose sunscreens that rely on non-nanoized zinc oxide or titanium dioxide. 12:100-7) require employers to provide similar information and training to their employees. [35], Ecotoxicity: Benzophenone is toxic to aquatic organisms. Unable to display Facebook posts.Show errorfunction cffShowError() { document.getElementById("cff-error-reason").style.display = "block"; document.getElementById("cff-show-error").style.display = "none"; }, A project of Breast Cancer Prevention Partners. [32], Irritation: Studies show that sunscreen products formulated with concentrations of up to 6 percent of oxybenzone rarely led to allergic reactions—in fact, only about 7/10,000 people had an allergic reaction in one study. [15], The evidence linking benzophenone and different derivatives to endocrine disruption is complex, and research suggests that different benzophenones have different endocrine effects. In personal care products, benzophenone is used as a fragrance enhancer or to prevent products such as soaps from losing scents and colors in the presence of UV light. The solubility of salt in water does not vary appreciably with temperature, NaCl is an electrolyte that is commonly used to melt ice by lowering its melting point. CAS no. Define the following terms clearly and concisely. Define the following terms clearly and concisely. The K, for H,O is 1.86 °C/m 4. [9] Benzophenone and oxybenzone are also used in nail polish, and lip balm. 1. In most cases, concentrations present low hazards to aquatic systems. Derivatives of benzophenone, such as benzophenone-2 (BP2) and oxybenzone (benzophenone-3 or BP3) are common ingredients in sunscreen. Benzophenone is used in personal care products such as lip balm and nail polish to protect the products from UV light. Biphenyl occurs naturally in coal tar, crude oil, and natural gas. [24] Although the evidence is mixed with regard to oxybenzone’s capacity to mimic estrogen, it can be converted into other forms that exhibit estrogenic potencies such as BP8 and 2,4,4’-trihydroxy-benzophenone (THB). CAS no. List the CAS number and hazards associated with benzophenone, C_13 H_18 O. For more detailed information, please visit ECHA C&L website. [13], Endocrine disruption: Benzophenone and its derived chemicals may influence the endocrine system. [28], Organ System Toxicity: The European Food Safety Authority (EFSA) classifies benzophenone as a known toxicant because benzophenone can cause liver hypertrophy in the rat at lower doses. Oxybenzone is a sunscreen ingredient associated with photoallergic reactions. [36] Oxybenzone is persistent and can collect in fat. [27] In addition, BP4 interferes with the expression of genes that control sex hormones in zebrafish, a species widely used to measure endocrine activity of substances. [9] Benzophenone and oxybenzone are also used in nail polish, and lip balm. Sodium borohydride is a white to grayish crystalline powder. Some studies indicate that the benzophenone derivative, oxybenzone, can elicit strong anti-androgenic activities in a human breast carcinoma cell line MDA-kb2.

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