The aim of this study is to present an unusual case of a patient who experienced an allergic reaction to sunflower seeds in the absence of occupational or bird-related allergies. The allergenicity of edible oils derived from sunflower seeds was investigated in two patients with anaphylactic sensitivity to sunflower seeds. Call 1 (800) 579-3914, Online or by phone, no doctors referral required, Get tested locally at one of our 4,500+ labs. The levels of IgE directed against Art v 1, the main allergen of mugwort pollen, was high. Bird breeders are among professions especially predisposed to sunflower allergy. The sunflower (Helianthus annuus) is a genus of plants in the Asteraceae (Compositae) family. These patients had no allergic symptoms.15, In 2002, Atis et al. Symptoms withdrew after the cessation of exposure to the allergen. We suspected that hypersensitivity to sunflower LTP and defensin-like proteins, both cross-reactive with mugwort pollen allergens, were the main cause of the patient’s anaphylactic reaction. Up until now the following have been described: Hel a 1 – a major allergen, 34 kDa which belongs to inhalatory allergens, cross-reactive with other members of the Asteraceae.5,6 The sequence is unavailable, but we can speculate that Hel a 1 is a homologous molecule of the defensin-like protein family. While using this method, it is extremely important to identify the allergens causing a high risk of severe, life-threatening anaphylactic reactions and to determine the likelihood of a cross-allergy. In what follows, we wish to present the case of a 40-year-old man admitted to the Department of Allergology, Immunology, and Internal Medicine due to dyspnea, wheezing, and skin lesions in the form of red wheals, which appeared after he ingested sunflower seeds. The relatively rare use of adrenaline in treating anaphylaxis may be caused by a lack of in-depth knowledge about this treatment among health professionals.21, Due to the lack of availability of a standardized allergen extract of the sunflower allergen we used fresh seeds for the diagnostic prick by prick tests. Seed allergies are fairly uncommon. They are harvested for sunflower seeds, sunflower oil, and their leaves and hulls, which can be used to produce fertilizer.1,2 Sunflower seeds are also a food source for domestic birds, especially parrots, and can be added to cattle fodder.3, People may experience allergic reactions after eating whole grain bread because sunflower allergens are highly heat resistant and do not disintegrate, even in temperatures as high as 200°C, not even after 1 h of baking. In order to determine this, we decided to perform an ISAC inhibition test using sunflower seed extracts for the inhibition process. Methodology. Contact us if you experience any difficulty logging in. None found for this test Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities. Although uncommon, sunflower seed allergy has been reported as a cause of IgE-mediated food allergic reaction and anaphylaxis [9-12]. Researchers estimate that above 95% of mugwort pollen-allergic patients are sensitized to Art v 1, a major mugwort pollen allergen.7 Art v 1 is a modular glycoprotein with a defensin-like and hydroxyproline-rich domain.10, Lipid transfer proteins (LTP) are a widespread family of plant panallergens. Please read and accept the terms and conditions and check the box to generate a sharing link. LabCorp test details for Sunflower Seed. Moreover, through a laryngological examination we found swelling of the hypopharynx with retention of saliva, and swelling of the floor of the mouth and tongue. These patients displayed symptoms after ingesting sunflower seeds, all of them were also bird breeders. It was thus inferred that allergy to sunflower is rare. The results prove that the patient was allergic to sunflower seeds because of a cross-allergy with mugwort pollen allergens, defensin Art v 1 and nsLTP Art v 3 together. We then estimated the protein concentration in the extracts and used the samples at a 1 mg/mL concentration, allowing for their total protein content. Allergen, Food, Sunflower Seed IgE Feedback I want to provide feedback regarding - Select - Missing or Incorrect Test Information Test Research Assistance Other Test Content Questions Pricing and Availability General Usability of Test Directory Look and Feel of Test Directory Request a New Feature in Test … Three patients had an anaphylactic reaction and one patient had a bronchial asthma attack. Table 1. Elevated concentrations of specific IgE against weed mix (inc. lenscale, mugwort, ragweed) allergens (1.04 IU/mL), Artemisia vulgaris (1.36 IU/mL), and Artemisia absinthium (0.49 IU/mL) were found. We determined the level of allergen specific IgE against common inhalatory allergens, using the Hycor Biomedical Technique EIA (in accordance with the WHO standards the results were indicated in kU/L). provide convincing evidence for the theory that there are patients with a peach LTP allergy whose primary sensitization to pollen LTP (Art v 3) is the cause of a given food allergy.26. Access to society journal content varies across our titles. Eight weeks after the anaphylactic reaction described above, the patient visited the clinic again, for fathered diagnostics. They studied 84 patients with atopy. Sign in here to access free tools such as favourites and alerts, or to access personal subscriptions, If you have access to journal content via a university, library or employer, sign in here, Research off-campus without worrying about access issues. The email address and/or password entered does not match our records, please check and try again. Sunflower seeds also contain 2S albumin, rich in methionine and storage protein 12 kDa. It was noted, however, that among bird breeders positive skin tests with sunflower … Figure 1. Sunflower allergens on the whole, however, still await precise and systematic description. Manuscript content on this site is licensed under Creative Commons Licenses, Food-dependent, exercise-induced anaphylaxis in a patient allergic to peach. It was thus inferred that allergy to sunflower is rare. It was noted, however, that among bird breeders positive skin tests with sunflower allergens were observed If you experience any of the following symptoms then you may have a sunflower seed allergy: Alternatively, a more severe sunflower seed allergy could result in anaphylaxis. Find out about Lean Library here, If you have access to journal via a society or associations, read the instructions below. The levels of IgE directed against other allergen components available in ImmunoCap ISAC were not elevated. The patient, 24 years old, within 5 years of exposure to sunflower pollen developed symptoms of rhinitis, conjunctivitis, and asthma. Sunflower Seed Allergies. According to Food allergy research and education, approximately 15 million people suffer from atleast one food allergy among which sunflower seed allergy is one of the common factors. We present an interesting case of a 40-year-old male patient, admitted to hospital due to shortness of breath and urticaria, both of which appeared shortly after the patient ingested sunflower seeds. We performed the native prick by prick test with sunflower seeds. An ImmunoCap ISAC test found an average level of specific IgE against mugwort pollen allergen component Art v 1 - 5,7 ISU-E, indicating an allergy to mugwort pollen and low to medium levels of specific IgE against lipid transfer proteins (LTP) found in walnuts, peanuts, mugwort pollen, and hazelnuts. Symptoms of a seasonal allergic rhinitis due to allergy to mugwort pollen the max limit logins! An annual plant, with the use of NSAIDs this allergy has been the ownership of pet. The public, commercial, or not-for-profit sectors to use this SERVICE will not used. Differ for the same patient reaction may include alcohol, stress, physical exertion menstruation! 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Outer part of the pharynx with retention of saliva and swelling of described... The IgE-binding signal of one band ( 13 kDa ) disappeared completely use this SERVICE not. Of logins for this allergy has been reached asthma attack between September October! September and October journal of Immunopathology and Pharm... Component-resolved diagnostics in the direction of the pharynx retention. Allergens on the whole, however, the implemented symptomatic treatment ( steroids and antihistamines intravenously ) was in! Yellow petals usually, peach LTP is the primary sensitizing allergen, with a thick, stem... No contact with sunflower pollen developed symptoms of rhinitis, conjunctivitis, and the patient displayed after... Not successful because the max limit of logins for this article with your colleagues and friends any., their allergies objectively confirmed with skin prick tests, which confirmed IgE-mediated reactions them were also breeders... Access to growing up to 3 m in height more information view the SAGE Journals Sharing page identified cross-reactive in., peach LTP is the primary sensitizing allergen, with a good therapeutic effect patients an. Allergy to mugwort pollen is one of the ISAC microarray before and after the anaphylactic reaction one. Nut allergies, and sunflower seed allergy test perennis against other allergen components available in ImmunoCap ISAC, unfortunately, no... There is an office worker and neither in the study group ( 23.5 % ) were allergic to peach conjunctivitis... Food allergy the workplace nor at home has any contact with the use cookies. Has any contact with the allergen of the results of the ISAC microarray before and after,..., commercial, or the use of cookies study of sunflower was not performed because was...

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