The toxicokinetic behavior, metabolism and elimination of formic acid, formate salts and methanol as a formic acid precursor was extensively studied in several species including humans, and there are significant species differences. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. The quality and correctness of the information remains the responsibility of the data submitter. Note: Registrants can also select ‘other’ as the type of density. Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. By summarising the endpoint study data, ECHA aims to make this information accessible in a user-friendly way in line with the Agency’s goals and standards. If so, the data provided is not processed for the Brief Profile. Different classifications can also be due to technical errors made during the notification process. Data is generally standardised and displayed in milligram per kilo soil (dry weight). EC number: 200-579-1 | CAS number: 64-18-6. Fusce eget lorem sed purus tempus blandit. Particle size distribution (Granulometry), Solubility in organic solvents / fat solubility, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Biodegradation in water and sediment: simulation tests, Additional information on environmental fate and behaviour, Short-term toxicity to aquatic invertebrates, Long-term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria, Toxicity to aquatic plants other than algae, Endocrine disrupter testing in aquatic vertebrates – in vivo, Toxicity to soil macroorganisms except arthropods, Endocrine disrupter mammalian screening – in vivo (level 3), Direct observations: clinical cases, poisoning incidents and other, Exposure related observations in humans: other data, Additional physico-chemical properties of nanomaterials, Toxicokinetics, metabolism and distribution. The CLP regulatory processes identified for the Brief Profile are: The BPR (528/2012) entered into force on 1 September 2013. Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. This allows a read across results between different forms of formates. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Skin irritation/corrosion provides substance information on the substance’s irritation/corrosion effect on the skin. Solid formic acid, which can exist in either of two polymorphs, consists of an effectively e… This is “Appendix C: Dissociation Constants and pKa Values for Acids at 25°C”, appendix 3 from the book Principles of General Chemistry (v. 1.0). This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. formic acid … % C&L Inventory . Pre-registration allows companies to continue manufacturing and importing their. Data is generally displayed in milligrams per kilogram, per bodyweight per day. Formic-d acid 95 wt. For substance’s physical state at 20°C and 1013 hPa, registrants can classify their substance as: This section provides an overview of the type of study records behind the presented results and – if applicable - data–waving justifications. This section summarises the partition coefficient values from all registered dossiers for the substance. Dermal route provides substance information on the substance’s acute toxicity via the dermal route. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Close Find out more on how we use cookies. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. Translated names gives the names in different EU languages, where available to ECHA. Half-life in air provides substance information on the substance’s dissipation half-life in air in seconds/minutes/hours/days/weeks/months/years. CAS names gives the name(s) provided to ECHA by the Chemical Abstracts Service, a division of the American Chemical Society, where available. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. EC10 / LC10 or NOEC for freshwater algae provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater algea or the no observed effect concentration for freshwater algae. This reflects the species differences in the hepatic concentrations of folates and folate-dependent enzymes which affect the formate degradation to CO2. Das Kohlenstoffatom hat eine Oxidationsstufe von +2. This section summarises the values related to toxicity to (terrestrial) plants from all registered dossiers for the substance. The most acidic proton is on the phenol group, so if the compound were to be reacted with a single molar equivalent of strong base, this is the proton that would be donated first. Short-term EC50 or LC50 for terrestrial plants provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of the terrestrial plants in the test, generally displayed in milligram per kilo soil (dry weight). What is the Ka of formic acid? The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Study data not processed for brief profile. machine wash liquids/detergents, automotive care products, paints and coating or adhesives, fragrances and air fresheners), outdoor use, outdoor use in long-life materials with low release rate (e.g. SMILES notations are comprised of atoms (designated by elemental symbols), bonds, parentheses (used to show branching), and numbers (used for cyclic structures). See the official IUPAC website for more information on the International Union of Pure and Applied Chemistry. Substance classifications under CLH are agreed at the Community level. Discussion on bioaccumulation potential result: The water soluble formic acid and formate salts rapidly dissociate in aqueous solutions (water, body fluids) to formate and the cation ( H+or Na+,K+,NH4+, etc.).

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